USC researchers reverse aging liver cells, cut Alzheimer’s protein in half

USC researchers have discovered that rejuvenating liver cells may protect against Alzheimer’s disease and heart disease.

In a study with rats, an experimental drug restored aged liver cells, halving the amount of an Alzheimer’s‑linked protein and lowering low‑density lipoprotein cholesterol to levels seen in younger animals. The treatment also reactivated a previously unknown communication system that enables liver cells to clear harmful substances from the bloodstream.