First Global Guideline Sets Standards for Phage Therapy in Hard-to-Treat Infections

A new guideline for personalized bacteriophage therapy has been issued by an international working group headed by the German Society for Infectious Diseases (DGI). The document, aimed at standardising clinical use of phage cocktails, was produced in collaboration with a broad coalition of experts and stakeholders.

The guideline development involved 20 professional organisations, 18 international specialists, representatives from regulatory agencies and two patient advocacy groups. The collaborative effort sought to align scientific evidence, regulatory requirements and patient perspectives, providing a comprehensive framework for clinicians and researchers seeking to implement phage therapy in a personalised manner.

The publication marks a significant step toward integrating phage therapy into mainstream clinical practice, offering a structured approach that balances efficacy, safety and regulatory compliance while acknowledging patient needs.